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Diag.mdu.cos.005.01 - Nucleic Acid Isolation

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LANGFORD VETERINARY SERVICES Date:2010 Rev. 2015 CONTROL OF SUBSTANCES HAZARDOUS TO HEALTH REGULATIONS (COSHH) ASSESSMENT – Dishwasher Divisional Manager: Cross referenced assessments: Alf Jarecki (e.g. SAH 2,4, 9. Surgery 15) Owner (Doc Author): D.Morris Diag.MDU.Gen.007 Diag.MDU.Gen.008 Responsible Person: D.Morris Assessment ID Reference: Diag.MDU.Cos.010.1 First Issued date: Last Revision date: 21 Dec 2015 *Stock Checker: 1. Division: Labs, MDU 2.Workers most at risk (print): Diagnostic Lab MDU registered staff 3. Room or Space: Churchill Building, Ada Irvine Suite, rooms 129 Guidance notes are provided overleaf. Read notes a, b and c before filling in the form. 4. Aim of Procedure: Cleaning of equipment used within the extraction laboratory. 5. Brief details of Procedure: Dishwasher is loaded with items, mainly waste collection blocks, reagent reservoirs and racks. A small amount of powder is added to the machine each run, the machine is run according to prescribed protocol. Salt and rinse aid are added as and when required. 6. Substances used, hazards identified and risks assessed: Dishwasher powder detergent: Irritating to eyes, people with sensitive or damaged skin should avoid prolonged contact. Dishwasher salt: None Rinse Aid: None All risks are considered minimal providing all control measures and training are followed. 7. Sources of information Reckitt Benckiser MSDS 8. Has a less hazardous alternative been considered? Hazards are considered low. 9. Control measures to be adopted for handling and use: Laboratory PPE, including coat and gloves. Good laboratory practice. Do not mix with other products. 10. Required checks and their frequency, on the adequacy and maintenance of control measures during the course of the procedure: None. 11. Disposal procedures during and at the end of the procedure: All materials are dilute and disposed of through the normal waste liquid route. EMERGENCY ACTIONS 12. Spillage or uncontrolled release: Small spillages should be cleared using a damp paper towel. Diag.MDU.Cos.010.1 13. First Aid: All individuals should be aware of local registered first aid contacts and procedures. If a member of staff is not aware of first aid procedures, immediate discussion with the local health and safety officer and/or management should take place. Dishwasher detergent and Rinse Aid Eye contact: Wash eyes with a large amount of water, for at least 15 minutes and seek medical attention. Skin contact: Wash off skin with plenty of water. Inhalation: Move person to fresh air. If breathing difficulties are experienced, seek medical attention. Ingestion: Rinse mouth. Do not induce vomiting. Drink plenty of water. Seek medical attention or a poisons information centre Dishwasher salt Eye contact: Rinse immediately with plenty of water, for at least 15 minutes. Skin contact: Wash skin with water. Inhalation: Move person to fresh air. Ingestion: Clean mouth with water. Drink plenty of water. Name of Assessor/Status D.Morris Name of Manager/Supervisor Date: ............................... Date: 21 Dec 2015 Signed: .......................... Signed: Alf Jarecki Name of CEO Richard Hammond Date: .............................. Signed: .......................... SEND A COMPLETED COPY OF THE FORM TO THE SAFETY OFFICER, ONE TO THE DIVISIONAL MANAGER AND KEEP ONE ON DISPLAY IN THE LABORATORY/WORK AREA, OR AVAILABLE IN A RING FILE MARKED 'COSHH ASSESSMENTS'. Diag.MDU.Cos.010.1 CONTROL OF SUBSTANCES HAZARDOUS TO HEALTH (COSHH) ASSESSMENTS GUIDANCE NOTES: "The main objective of the COSHH regulations is to reduce occupational ill health by setting out a simple framework for controlling substances hazardous to health in the workplace." HSE. a. To comply with Health and Safety laws a COSHH assessment must be carried out by or on behalf of the project leader before beginning an experiment or procedure. This is to assess the potential risks of any chemicals or agents (including micro-organisms, allergens and dusts) to those involved in the procedure. b. Help in completing the form can be obtained from Area Safety Representatives, the Departmental Safety Supervisor or the College Safety Officer. COSHH information on chemicals is found in the BDH Hazard Data Sheets, Sigma/Aldrich Library of Chemical Safety Data, and Martindale, the Extra Pharmacopoeia held by the Departmental Safety Supervisor. c. When the form is complete it must be signed by the appropriate members of academic staff, the Head of Department and photocopied. Give one copy to the College Safety Officer, one to the Departmental Safety Supervisor and keep the one in the ring folder in a prominent place in the laboratory or work area. If experimental animals are involved a copy is also required by the Manager of Biological Services. d. List the briefest details or official names of the techniques used in the experiment or procedure are necessary. For example PAGE Electrophoresis, PCR Procedures, etc. e. The hazardous substances used and their risks should be listed. They may often be grouped by hazard, for example Acids and Alkalis as corrosive. Substances need only be mentioned if present at a level to create a risk. Unusually toxic or hazardous substances should be assessed separately. f. A safer alternative substance should be used whenever possible. Often a technique or procedure is used because of tradition or habit. If an alternative one is available and does not compromise the accuracy, precision or sensitivity of the procedure it should be used. g. Control measures must be employed for the safe handling of hazardous substances. The control measures recommended should be used and if not available an alternative procedure found for Diag.MDU.Cos.010.1 which control is available. Eye protection is generally required in all chemical laboratories. It is recommended that gloves and/or a face visor should be worn if a fume cupboard is used. Monitoring equipment should be available if Maximum Exposure Limits (MEL) exist for a substance. h. Surveillance of workers is necessary when working with certain toxic substances which cause occupational ill-health. These substances are listed in EH40 and COSHH regulations (see below). Equipment, both electrical and mechanical, requires maintenance and frequent checking especially if personal safety depends on them. i. All staff working with animals are required to complete a questionnaire about their personal health in compliance with occupational health regulations. j. Negative pressure units, i.e. fume cupboards, class II cabinets etc, require at least one annual performance check and service. Records of such inspections must be kept. k. Pregnant women and women intending to become pregnant should be advised of the hazards of working with carcinogens, teratogens, mutagens, steroid hormones, radioactive substances, certain pathogens, large animals and carrying heavy objects. Work activities should be reorganised to minimise health risks to them during pregnancy. HSE Publications A Step by Step Guide to COSHH Assessment [(HS(G)97, (1993)] Occupational Exposure Limits (EH40, revised annually) General COSHH Approved Code of Practice [L5, (1995)]