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Leica Application Suite

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Leica Application Suite Integrated Software Solutions You’re In Focus! Totally Integrated Solution Leica Application Suite (LAS) integrates Leica automated microscopes, macroscopes, digital cameras and software into one common environment to provide an easy to use and consistent imaging solution with unrivalled performance. The versatility of the Leica Application Suite means that it is suitable for a diverse range of life science and industrial applications such as materials quality control, pathology, pharmaceutical testing and many other laboratory tasks. LAS accelerates the visualisation, enhancement, measurement and documentation of digital images through the richness of its image processing functions. This powerful software solution can control all functions of the Leica DM range of upright and inverted Compound Microscopes and motorised Stereo-microscopes and Macroscopes. By providing all the necessary tools for the installed applications to communicate with each other as well as with peripheral devices connected to the computer, LAS offers an intuitive solution that simplifies routine and research analysis. Features at a glance: • A unique user interface designed for ultimate operator convenience and for all imaging software applications. • Increases productivity by integrating microscopes, digital cameras and application software to co-ordinate imaging tasks with intelligent control. • Automates digital-microphotography environment through the computerised features of the Leica microscopes. • A single application for acquiring, storing, annotating and displaying high quality images with a thumbnail gallery. • High modularity starting from routine applications to cutting edge research procedures. • LAS is based on Windows PCs and provides a cost-effective and uniform environment, compatible across the Leica range of microscopes and Digital FireWire cameras. Demanding Microscopy! The common core functionality of Leica Application Suite creates an intelligent and automated micro-imaging environment and is supplied with each Leica microscope and digital camera as part of an integrated system solution. This provides the basic software for configuration and control as well as for the acquisition, analysis and processing of high quality digital images. The core package includes the following features: Features at a glance: • Microscope and digital camera configuration and control in a fully integrated manner. • Basic annotation tools to allow image data and measurement data to be added in order to indicate relevant details. • Auto and manual exposure adjustments to allow fully optimised imaging conditions. • A thumbnail gallery of acquired images which can be reviewed quickly and easily. • Calibrations are calculated, based on data read from Leica microscopes and cameras and a scale bar indicates image size. Now scientists can spend 100% of their time concentrating on their work and not on their tools. Rouven Heeb, Design Engineer Leica SMS 3 LAS offers you a higher precision image system for Christian Wild, Development Engineer Leica SMS Attention to Detail! The professional design of LAS offers a unique user interface that uses a workflow organisation in order to create the ultimate working environment based on user convenience. Setup The setup task bar provides a straightforward method of configuring the Leica microscope and camera to be used during image acquisition. All configurations such as establishing objective types and filter descriptions can be readily saved and recalled to ensure that imaging conditions are correctly reproduced. Acquire LAS enables the easy acquisition of images, which can be subsequently added to a Gallery and stored in a defined folder. With LAS, all camera controls can be set to individual requirements from exposure, gain and gamma, to histogram black and white levels. Images can be acquired in a variety of sizes, colour depths and file formats to provide even more flexibility. By setting the sharp image option and shading reference from the processing toolbar, images can be acquired at the highest detail necessary so that further processing requirements are minimal. Leica Application Suite also allows a focusing region to be defined on a live image so that areas of significance can be easily identified and focussed more rapidly. All parameters and configurations can be saved and recalled at a later date. * For more advanced acquisition options, additional modules can be added such as LAS MultiFocus, LAS Montage, LAS Image Overlay, LAS MultiStep and LAS MultiTime Timelapse and Movie Recording. Browse The Browse function provides access to all associated information for each stored image such as the time of acquisition, the bit depth and the calibration. The directory browser means that images can be located quickly and easily through a simple navigation system whereby folders can be effortlessly located. The integrated gallery stores each image as a thumbnail to speed up the process of locating and retrieving image files. Furthermore, images can be copied and pasted to other applications, or zoomed and panned for a more detailed inspection. * To further improve the browsing capabilities and search functions of LAS, the optional Image Organizer is available. Process By using the Process workflow tab, images can be further enhanced and refined. From brightness and saturation levels to contrast and gamma, each image can be adjusted to your requirements. Additionally, the basic annotation tools mean that a file name, the time of acquisition and a brief description can be included to provide concise information. Even scale bars and lines can be added and individually customized. Annotations can either be saved with the image of merged with it so that the data is still visible when exported. * To further enhance this functionality, the LAS Extended Annotation module can be added to your system These underlying capabilities can be enhanced with a range of advanced modules and applications to form a powerful microscopy imaging environment. Each LAS module provides the flexibility to tailor a system solution to fulfil individual needs with upgrade options available for future requirements further analysis and quantification. Imaging Modules To Suite Your Needs MULTIFOCUS The LAS Multifocus module is designed to easily create extended depth of field images from a series of partially focused images by providing fully integrated control of microscopes with motorized focus. Exposure, gain and shading can be individually set for user convenience. MONTAGE AND 3D VIEWER The LAS Montage module is a powerful solution for creating and visualising extended focus images. The extensive range of methods in conjunction with the preview capability makes LAS Montage a premier solution for extended focus image creation. IMAGE OVERLAY The LAS Image Overlay module is designed for multi-channel fluorescent imaging, performing tasks in a simple and automatic manner. From visualization through to enhancements and the documentation of images, LAS Image Overlay provides a highly professional application. MULTITIME – TIMELAPSE AND MOVIE The LAS MultiTime module is a highly effective solution for the automatic acquisition of images at intervals from seconds to minutes. With its movie recording functionality, the LAS MultiTime module provides a simple method of acquiring a compressed image stream directly to the hard drive. MULTISTEP LAS MultiStep is a highly intelligent module that when used with a Leica microscope, motorized scanning stage and digital camera, automatically acquires images at XY positions defined by a rectangular pattern. Mosaic images can be created and manipulated and reduced in size in to more manageable dimensions. IMAGE ORGANIZER The LAS Image Organizer application saves and retrieves data effortlessly in freely defined categories. Intelligent search functions simplify the process of finding and retrieving information. With its integrated store and recall function the microscope and camera settings can be easily restored. STORE & RECALL The Store & Recall module allows you to benefit from the full digital integration of microscope and camera. Your results will be completely reproducible including e.g. light settings, contrasting method, magnification, exposure time and many more. MULTIUSER PACKAGE You and other microscope users can create individual microscope profiles which are optimized for your samples and applications. A user profilee not only covers all microscope accessories, including objectives andfilter cubes, but also accommodates your special personal settings. An Integrated Microscopy Solution EXTENDED ANNOTATION LAS Extended Annotation module that allows text and graphical elements to be added directly to an image including lines, arrows, shapes images, times and text. All annotations can be customized to individual requirements. INTERACTIVE MEASUREMENT The Leica Application Suite Interactive Measurement Module is designed to perform sophisticated measurements on areas of interest. Furthermore, objects can be counted individually and assigned to a labeled class. STEEL EXPERT Leica Steel Expert is a highly specialised software programme for automatic steel inclusion rating. This module is a powerful software solution that brings fast, reproducible and accurate results to the process of automated inclusion rating for stainless steel alloys. RETICULE The LAS Reticule application provides electronic means of viewing live images and overlaying reticule styles to provide visual feedback as to the approximate scale of the field of view. Object size comparisons and point counting measurements quickly and easily. DIGITAL AUTOFOCUS The Digital Autofocus module provides a precise focus position for your sample. You always get excellent results since the performance with respect tospeed and accuracy is optimized for each objective. Besides being highly convenient, the module is also cost effective because no additional gadgets are needed. If there is no CD-ROM inside please contact your local dealer or go to www.leica-microsystems.com/LAS to download the files. ica Le em s.c om © M icr os ys tem s( Sw it z er land ) Ltd. z , CH-943 5 Heerbrugg, (Swit eic w.l ww , ) d erlan os ic r a-m t ys Leica Microsystems – the brand for outstanding products Leica Microsystems’ mission is to be the world’s first-choice provider of innovative solutions to our customers’ needs for vision, measurement and analysis of microstructures. The companies of the Leica Microsystems Group operate internationally in three business segments, where we rank with the market leaders. Leica, the leading brand for microscopes and scientific instruments, developed from five brand names, all with a long tradition: Wild, Leitz, Reichert, Jung and Cambridge Instruments. Yet Leica symbolizes innovation as well as tradition. • Microscopy Systems Australia: Austria: Canada: Denmark: France: Germany: Italy: Japan: Korea: Netherlands: People’s Rep. of China: Portugal: Singapore Spain: Sweden: Switzerland: United Kingdom: USA: Gladesville Vienna Richmond Hill/Ontario Herlev Rueil-Malmaison Bensheim Milan Tokyo Seoul Rijswijk Hong Kong Lisbon Barcelona Sollentuna Glattbrugg Milton Keynes Bannockburn/lllinois Tel. +61 2 9879 9700 Tel. +43 1 486 80 50 0 Tel. +1 905 762 2000 Tel. +45 4454 0101 Tel. +33 1 47 32 85 85 Tel. +49 6251 136 0 Tel. +39 0257 486.1 Tel. + 81 3 5421 2800 Tel. +82 2 514 65 43 Tel. +31 70 4132 100 Tel. +852 2564 6699 Tel. +351 21 388 9112 Tel. +65 6779 7823 Tel. +34 93 494 95 30 Tel. +46 8 625 45 45 Tel. +41 44 809 34 34 Tel. +44 1908 246 246 Tel. +1 847 405 0123 Fax +61 2 9817 8358 Fax +43 1 486 80 50 30 Fax +1 905 762 8937 Fax +45 4454 0111 Fax +33 1 47 32 85 86 Fax +49 6251 136 155 Fax +39 0257 40 3475 Fax +81 3 5421 2896 Fax +82 2 514 65 48 Fax +31 70 4132 109 Fax +852 2564 4163 Fax +351 21 385 4668 Fax +65 6773 0628 Fax +34 93 494 95 32 Fax +46 8 625 45 10 Fax +41 44 809 34 44 Fax +44 1908 609 992 Fax +1 847 405 0164 and representatives of Leica Microsystems in more than 100 countries. In accordance with the ISO 9001 certificate, Leica Microsystems (Switzerland) Ltd, Business Unit Stereo & Macroscope Systems has at its disposal a management system that meets the requirements of the international standard for quality management. In addition, production meets the requirements of the international standard ISO 14001 for environmental management. www.leica-microsystems.com • Specimen Preparation We provide comprehensive systems and services for clinical histo- and cytopathology applications, biomedical research and industrial quality assurance. Our product range includes instruments, systems and consumables for tissue infiltration and embedding, microtomes and cryostats as well as automated stainers and coverslippers. • Medical Equipment Innovative technologies in our surgical microscopes offer new therapeutic approaches in microsurgery. Illustrations, descriptions and technical data are not binding and may be changed without notice. Printed on chlorine-free paper with a high content of recycled fibre. M1-525-0en • © Leica Microsystems (Switzerland) Ltd • CH-9435 Heerbrugg, 2006 • Printed in Switzerland – V.2006 – RDV Leica Microsystems – an international company with a strong network of customer services Our expertise in microscopy is the basis for all our solutions for visualization, measurement and analysis of microstructures in life sciences and industry. With confocal laser technology and image analysis systems, we provide three-dimensional viewing facilities and offer new solutions for cytogenetics, pathology and materials sciences.