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Topnet: A Tool For Comparing Biological Sub

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Mann Library on November 11, 2010 C*$%8#". !"#$%&# '#&() *%)%+,#-. /001. 23$4 5/. !34 6 !!( #7 %*+0 '#5% *, 4#,$ #7 $0% "%*- '%$=#"1, *"% $## +#4)-%< $# 5&,+%"' *'. &'7#"4*$&#' 7"#4 * 8-#:*- /&%=2 d)%+&D+*--.6 &' $0% .%*,$ )"#$%&'()"#$%&' &'$%"*+$&#' '%$=#"1 %<*4)-%6 5&77%"9 %'$ +#-#", *"% ;,%5 $# &'5&+*$% $0% ,#;"+%, #7 $0% &'$%"*+$&#' :%$=%%' * 8&/%' '#5% *'5 $0% +%'$%" '#5%2 M'$%"*+$&#', $0*$ *"% +#'D"4%5 :. ,%/%"*- &'5%)%'5%'$ 4%$0#5, 0*/%' :%%' ,0#=' $# :% #7 0&80%" G;*-&$. >@gA2 B#)f%$ +*' $0;, 7*+&-&$*$% $0% 5%$%"4&'*$&#' #7 "%-&*:-% &'$%"*+$&#' )*"$'%", #7 * ,)%+&D+ 8%'% 7#" ;,% &' 7;"$0%" &'/%,$&8*$&#'2 2&)"+$&P+E&3=4 I&'*--.6 *, 5&,+;,,%5 *:#/%6 &$ &, 0*"5 $# 5%)&+$ $0% =0#-% '%$=#"1 +-%*"-.2 3-$0#;80 &$ &, ;,%7;- $# ,0#= *-- $0% '%&80:#", #7 %*+0 '#5%6 $0% ;,%" ,#4%$&4%, =*'$, $# 5&"%+$-. /&%= $0% $#)#-#8. #7 * ,;:9'%$=#"16 =0%"% $0% )"#$%&', $0*$ $0% ;,%" &, &'$%"%,$%5 &' *"% &'/#-/%52 Z,&'8 B#)f%$6 $0% ;,%" +#;-5 ,)%+&7. $=# '#5%, *'5 * 4*<&4;4 )*$0 -%'8$02 B0%' $0% $##- =&-- ,0#= *-- )#,,&:-% )*$0, +#''%+$&'8 $0%,% '#5%, >*, ,0#=' &' I&82 ?6 b/&,;*-&H*$&#'KA =&$0 -%'8$0 -%,, $0*' $0% ,)%+&D%5 4*<&4;42 =01%&+#.>, +* 4%3!"# 7&)E+=#% #+$#"$+E&3=4 B# +*-+;-*$% $0% 5&*4%$%" *'5 $0% +0*"*+$%"&,$&+ )*$0 -%'8$0 #7 %*+0 '%$=#"1 >#" ,;:9'%$=#"1A6 5&,$*'+%, :%$=%%' *'. $=# +#''%+$%5 '#5%, >5&,+#''%+$%5 '#5%, *"% %<+-;5%5A *"% +*-+;-*$%5 D",$ :. * 8"%%5. *-8#"&$042 d&4)-. );$6 7#" %*+0 ,#;"+% '#5%6 *-- #7 &$, '%&80:#", *"% -*:%-%5 *, 0*/&'8 * 5&,$*'+% #7 ?2 B0% '#5%, $0*$ *"% -&'1%5 $# $0%,% '%&80:#", *"% -*:%-%5 *, 0*/&'8 * 5&,$*'+% #7 @6 *'5 ,# #'6 ;'$&- $0% D'*- '#5% &, %'+#;'$%"%52 f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a. ,+#"&'8 %*+0 '#5% =&$0 &$, ,0#"$%,$ 5&,$*'+% 7"#4 :#$0 ,#;"+% *'5 $*"8%$6 =% +*' ;,% $0% "%-*$&#' :%$=%%' $0% ,+#"%, #7 * '#5% *'5 $0% ,+#"%, #7 &$, '%&80:#", $# &5%'$&7. %58%, #' * ,0#"$%,$ )*$0 &' $&4% )"#)#"$&#'*- $# $0% ';4:%" #7 %58%, &' $0% 8"*)02 O-3&#%) &= %MQ%((&=> + )"QR=%ES3,? &= $+,>%, =%ES3,?4 B0% );")#,% #7 B#)f%$ &, $# *--#= $0% "%,%*"+0%" $# 5&/&5% $0% '%$=#"1 #7 &'$%"%,$ &'$# 4*'. ,;:9'%$=#"1,6 *'5 $0%' +#4)*"% $#)#-#8&+*- ,$*$&,$&+, #7 $0#,% ,;:9'%$=#"1,2 e#=%/%"6 $0% &,,;% #7 %4:%55&'8 * ,;:9'%$=#"1 &'$# * :&88%" '%$=#"1 0*, * Downloaded from nar.oxfordjournals.org at Albert R. Mann Library on November 11, 2010 ?+1@&" 67 i/%"/&%= #7 B#)f%$2 B0% =0#-% =%:,&$% +#',&,$, #7 7#;" 4*j#" )*"$,O ;)-#*56 +*-+;-*$&#'6 '*/&8*$&#' *'5 /&,;*-&H*$&#'2 I#" 5%$*&-,6 )-%*,% "%7%" $# $0% $%<$2 !!" !"#$%&# '#&() *%)%+,#-. /001. 23$4 5/. !34 6 =330+2-#+%*A -*-0B,+, %: (+::"&"*# 1"*%>+2 :"-#@&", +* B"-,# M' * 5&"%+$ 7*,0&#'6 =% +*' *))-. 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